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I am not saying believing that the brand new label diligently reflects the brand new belongings in new papers

21 Th9, 2022

Authors’ impulse

What’s the opportinity for determining timely-evolving and slow-evolving proteins-programming family genes? Should your method is only “Fool around with Ka”, I would argue that people have over one to before.

Authors’ response

I’ve altered the newest label so you’re able to “Nonsynonymous substitution rates (Ka) try a fairly uniform factor for defining fast-growing and sluggish-growing necessary protein-programming genes”. We have searched the fresh new relevant literary works cautiously and get maybe not located books that have complete including comprehensive critiques toward strategies.

Records

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Demuth JP, De- Bie T, Stajich JE, Cristianini N, Hahn MW: The newest advancement out-of mammalian gene group. PLoS One to. 2006, 1: e85-/record.pone.0000085.

Williamson SH, Hubisz MJ, Clark AG, Payseur BA, Bustamante Video game, Nielsen Roentgen: Localizing latest adaptive evolution about people genome. PLoS Genet. 2007, 3: e90-/record.pgen.0030090.

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Nielsen Roentgen, Bustamante C, Clark AG, Glanowski S, Sackton TB, Hubisz MJ, Fledel-Alon A, Tanenbaum DM, Civello D, White TJ, J Sninsky J, Adams MD, Cargill M: A scan to possess absolutely picked genetics throughout the genomes out-of humans and you can chimpanzees. PLoS Biol. 2005, 3: e170-/journal.pbio.0030170.

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